Dimethylglycine oxidase

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Template:Infobox enzyme In enzymology, a dimethylglycine oxidase (EC 1.5.3.10) is an enzyme that catalyzes the chemical reaction

N,N-dimethylglycine + H2O + O2 sarcosine + formaldehyde + H2O2

The 3 substrates of this enzyme are N,N-dimethylglycine, H2O, and O2, whereas its 3 products are sarcosine, formaldehyde, and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with oxygen as acceptor. The systematic name of this enzyme class is N,N-dimethylglycine:oxygen oxidoreductase (demethylating). It employs one cofactor, FAD.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB2, Template:PDB2, and Template:PDB2.

References

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