Dilazep
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Template:Short description Template:Drugbox
Dilazep is a vasodilator that acts as an adenosine reuptake inhibitor.[1][2]
It is used for the treatment of cardiopathy and renal disorders.[3]
Synthesis
The reaction of bis(3-hydroxypropyl)ethylene diamine (1) with 1-bromo-3-chloropropane (2) gives the homopiperazine derivative 3. Esterification by reaction with 3,4,5-trimethoxybenzoyl chloride (4) completes the synthesis of dilazep (5).[4][5][6]
See also
- Hexobendine, a drug with similar chemical structure
References
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- ↑ Thieme
- ↑ GB1107470 idem Herbert Arnold, Kurt Pahls, Rolf Rebling,Norbert Brock, Hans-Dieter Lenke, U.S. patent 3532685 (1970 to Asta Werke Ag Chem Fab)
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