DLX2

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Template:Short description Template:Infobox gene Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene.[1][2]

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.[2]

Interactions

DLX2 has been shown to interact with DLX5,[3] MSX1[3] and Msh homeobox 2.[3]

References

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Further reading

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