Cyclopentanone

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Cyclopentanone[1]
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Template:Longitem C5H8O
Molar mass 84.12 g/mol
Appearance clear, colorless liquid
Odor peppermint-like
Density 0.95 g/cm3, liquid
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Template:Longitem −51.63·10−6 cm3/mol
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Template:Longitem cyclohexanone
2-pentanone
3-pentanone
cyclopentenone
Template:Longitem cyclopropane

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Cyclopentanone is the organic compound with the formula (CH2)4CO. This cyclic ketone is a colorless volatile liquid.

Preparation

Ketonic decarboxylation of adipic acid gives cyclopentanone. The reaction is conducted at elevated temperatures in the presence of barium hydroxide.[3]

File:Barium adipate pyrolysis.png

The Pd-catalyzed oxidation of cyclopentene also gives cyclopentanone.[4]

Uses

Cyclopentanone is common precursor to fragrances, especially those related to jasmine and jasmone. Examples include 2-pentyl- and 2-heptylcyclopentanone.[5] It is a versatile synthetic intermediate, being a precursor to cyclopentobarbital.[6]

File:Cyclopal.svg
Cyclopentobarbital, a drug made from cyclopentanone

Cyclopentanone is also used to make cyclopentamine, the pesticide pencycuron, and pentethylcyclanone.[6]

It is also used as a precursor to cubane-1,4-dicarboxylate, which is used to synthesize other substituted cubanes, such as the high explosives heptanitrocubane and octanitrocubane.[7]

References

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  1. Merck Index, 11th Edition, 2748.
  2. Sigma-Aldrich Co., Cyclopentanone.
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  5. Johannes Panten and Horst Surburg "Flavors and Fragrances, 2. Aliphatic Compounds" in Ullmann's Encyclopedia of Industrial Chemistry, 2015, Wiley-VCH, Weinheim.Script error: No such module "CS1 identifiers".
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