ctRNA
In molecular biology ctRNA (counter-transcribed RNA) is a plasmid encoded noncoding RNA that binds to the mRNA of Template:Chem name and causes translational inhibition.[1] ctRNA is encoded by plasmids and functions in rolling circle replication to maintain a low copy number. In Corynebacterium glutamicum, it achieves this by antisense pairing with the mRNA of Template:Chem name, a replication initiation protein.[1] In Enterococcus faecium the plasmid pJB01 contains three open reading frames, copA, Template:Chem name, and Template:Chem name. The pJB01 ctRNA is coded on the opposite strand from the Template:Chem name/Template:Chem name intergenic region and partially overlaps an atypical ribosome binding site for Template:Chem name.[2]
See also
References
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