Core binding factor

Template:Short description The Core binding factor (CBF) is a group of heterodimeric transcription factors.

Core binding factors are composed of:

• a non-DNA-binding CBFβ chain (CBFB)
• a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3)

See also

• AI-10-49, an anti-leukemic drug under development.

External links

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