Complete protein

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A complete protein or whole protein is a food source of protein that contains an adequate proportion of each of the nine essential amino acids necessary in the human diet.[1][2][3][4][5]

Concept

Protein nutrition is complex because any proteinogenic amino acid may be the limiting factor in metabolism. Mixing livestock feeds can optimize for growth, or minimize cost while maintaining adequate growth. Similarly, human nutrition is subject to Liebig's law of the minimum: The lowest level of one of the essential amino acids will be the limiting factor in metabolism.

If the content of a single indispensable amino acid in the diet is less than the individual's requirement, then it will limit the utilization of other amino acids and thus prevent the normal rates of synthesis even when the total nitrogen intake level is adequate. Thus the "limiting amino acid" will determine the nutritional value of the total nitrogen or protein in the diet.[6]

Protein sources are thus rated by their limiting amino acids.[7]

Most people eat a varied diet with multiple sources of protein. Incomplete sources can complement each other and become complete when combined.[8] Combining does not need to happen for every single meal: so long as the diet is varied and meets caloric needs, even vegans and vegetarians – people who tend to have more "incomplete protein" in their diet – can easily meet their amino acid needs. In other words, most people do not need to consider the completeness of proteins of single foods.[9]

Amino acid profile

The following table lists the optimal profile of the nine essential amino acids in the human diet, which comprises complete protein, as recommended by the US Institute of Medicine's Food and Nutrition Board. The foodstuffs listed for comparison show the essential amino acid content per unit of the total protein of the food; 100g of spinach, for example, only contains 2.9g of protein (6% Daily Value), and of that protein 1.36% is tryptophan.[2][10](note that the examples have not been corrected for digestibility)

Essential amino acid mg/g of protein percentage of total protein raw, whole chicken egg[11] quinoa[12] raw spinach[13]
Tryptophan 7 0.7% 1.33% 1% 1.36%
Threonine 27 2.7% 4.42% 3.2% 4.27%
Isoleucine 25 2.5% 5.34% 4.2% 5.14%
Leucine 55 5.5% 8.65% 7.3% 7.8%
Lysine 51 5.1% 7.27% 6.1% 6.08%
Methionine+Cystine 25 2.5% 5.18% 2.7%+1.3% 1.85%+1.22%
Phenylalanine+Tyrosine 47 4.7% 9.39% 4.3%+3.6% 4.51%+3.78%
Valine 32 3.2% 6.83% 5% 5.63%
Histidine 18 1.8% 2.45% 3.1% 2.24%
Total 287 28.7% 50.86% 41.8% 43.88%

Total adult daily intake

The second column in the following table shows the amino acid requirements of adults as recommended by the World Health Organization[14] calculated for a Template:Convert adult. Recommended Daily Intake is based on Template:Convert per day,[15] which could be appropriate for a Template:Convert adult.

Essential amino acid Required mg/day for a Template:Convert adult
Tryptophan 248
Threonine 930
Isoleucine 1240
Leucine 2418
Lysine 1860
Methionine+Cystine 930
Phenylalanine+Tyrosine 1550
Valine 1612
Histidine 620
Total Template:Convert
Total Protein Template:Convert

See also

References

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  6. Food and Nutrition Board of Institute of Medicine (2005) Dietary Reference Intakes for Protein and Amino Acids, page 685, from National Academies Press
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