Chromosome 19

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Template:Short description Template:Infobox chromosome Chromosome 19 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 19 spans more than 61.7 million base pairs, the building material of DNA. It is considered the most gene-rich chromosome containing roughly 1,500 genes, despite accounting for only 2 percent of the human genome.[1][2]

Genes

Number of genes

The following are some of the gene count estimates of human chromosome 19. Because researchers use different approaches to genome annotation, their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.[3]

Estimated by Protein-coding genes Non-coding RNA genes Pseudogenes Source Release date
CCDS 1,357 — — [4] 2016-09-08
HGNC 1,372 299 413 [5] 2017-05-12
Ensembl 1,469 894 514 [6] 2017-03-29
UniProt 1,435 — — [7] 2018-02-28
NCBI 1,430 604 528 [8][9][10] 2017-05-19

Gene list

Script error: No such module "Category see also".Template:Category see also/Category pair check The following is a partial list of genes on human chromosome 19. For complete list, see the link in the infobox on the right. Script error: No such module "Template wrapper".Script error: No such module "Check for unknown parameters".

Short arm

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Long arm

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Diseases and disorders

The following diseases are some of those related to genes on chromosome 19:[13]

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Cytogenetic band

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G-bands of human chromosome 19 in resolution 850 bphs[16]
Chr. Arm[17] Band[18] ISCN
start[19] 		ISCN
stop[19] 		Basepair
start 		Basepair
stop 		Stain[20] Density
19 p 13.3 0 578 Script error: No such module "val". Script error: No such module "val". gneg
19 p 13.2 578 870 Script error: No such module "val". Script error: No such module "val". gpos 25
19 p 13.13 870 1034 Script error: No such module "val". Script error: No such module "val". gneg
19 p 13.12 1034 1216 Script error: No such module "val". Script error: No such module "val". gpos 25
19 p 13.11 1216 1581 Script error: No such module "val". Script error: No such module "val". gneg
19 p 12 1581 1809 Script error: No such module "val". Script error: No such module "val". gvar
19 p 11 1809 1992 Script error: No such module "val". Script error: No such module "val". acen
19 q 11 1992 2159 Script error: No such module "val". Script error: No such module "val". acen
19 q 12 2159 2372 Script error: No such module "val". Script error: No such module "val". gvar
19 q 13.11 2372 2569 Script error: No such module "val". Script error: No such module "val". gneg
19 q 13.12 2569 2737 Script error: No such module "val". Script error: No such module "val". gpos 25
19 q 13.13 2737 2949 Script error: No such module "val". Script error: No such module "val". gneg
19 q 13.2 2949 3101 Script error: No such module "val". Script error: No such module "val". gpos 25
19 q 13.31 3101 3193 Script error: No such module "val". Script error: No such module "val". gneg
19 q 13.32 3193 3390 Script error: No such module "val". Script error: No such module "val". gpos 25
19 q 13.33 3390 3649 Script error: No such module "val". Script error: No such module "val". gneg
19 q 13.41 3649 3770 Script error: No such module "val". Script error: No such module "val". gpos 25
19 q 13.42 3770 3938 Script error: No such module "val". Script error: No such module "val". gneg
19 q 13.43 3938 4120 Script error: No such module "val". Script error: No such module "val". gpos 25

References

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  1. ↑ Script error: No such module "citation/CS1".
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  13. ↑ Script error: No such module "Citation/CS1".
  14. ↑ Script error: No such module "citation/CS1".
  15. ↑ Script error: No such module "citation/CS1".
  16. ↑ Genome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26.
  17. ↑ "p": Short arm; "q": Long arm.
  18. ↑ For cytogenetic banding nomenclature, see article locus.
  19. ↑ a b These values (ISCN start/stop) are based on the length of bands/ideograms from the ISCN book, An International System for Human Cytogenetic Nomenclature (2013). Arbitrary unit.
  20. ↑ gpos: Region which is positively stained by G banding, generally AT-rich and gene poor; gneg: Region which is negatively stained by G banding, generally CG-rich and gene rich; acen Centromere. var: Variable region; stalk: Stalk.

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External links

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