Chromosome 18

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Template:Short description Template:Infobox chromosome Chromosome 18 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 18 spans about 80 million base pairs (the building material of DNA) and represents about 2.5 percent of the total DNA in cells.

Genes

Number of genes

The following are some of the gene count estimates of human chromosome 18. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.[1]

Estimated by Protein-coding genes Non-coding RNA genes Pseudogenes Source Release date
CCDS 261 — — [2] 2016-09-08
HGNC 262 138 241 [3] 2017-05-12
Ensembl 268 608 247 [4] 2017-03-29
UniProt 276 — — [5] 2018-02-28
NCBI 285 432 304 [6][7][8] 2017-05-19

Gene list

Script error: No such module "Category see also".Template:Category see also/Category pair check The following is a partial list of genes on human chromosome 18. For complete list, see the link in the infobox on the right. Script error: No such module "Template wrapper".Script error: No such module "Check for unknown parameters".

Diseases and disorders

The following diseases are some of those related to genes on chromosome 18:

Cytogenetic band

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G-bands of human chromosome 18 in resolution 850 bphs[10]
Chr. Arm[11] Band[12] ISCN
start[13] 		ISCN
stop[13] 		Basepair
start 		Basepair
stop 		Stain[14] Density
18 p 11.32 0 159 Script error: No such module "val". Script error: No such module "val". gneg
18 p 11.31 159 430 Script error: No such module "val". Script error: No such module "val". gpos 50
18 p 11.23 430 526 Script error: No such module "val". Script error: No such module "val". gneg
18 p 11.22 526 685 Script error: No such module "val". Script error: No such module "val". gpos 25
18 p 11.21 685 1035 Script error: No such module "val". Script error: No such module "val". gneg
18 p 11.1 1035 1290 Script error: No such module "val". Script error: No such module "val". acen
18 q 11.1 1290 1561 Script error: No such module "val". Script error: No such module "val". acen
18 q 11.2 1561 1847 Script error: No such module "val". Script error: No such module "val". gneg
18 q 12.1 1847 2229 Script error: No such module "val". Script error: No such module "val". gpos 100
18 q 12.2 2229 2436 Script error: No such module "val". Script error: No such module "val". gneg
18 q 12.3 2436 2755 Script error: No such module "val". Script error: No such module "val". gpos 75
18 q 21.1 2755 3153 Script error: No such module "val". Script error: No such module "val". gneg
18 q 21.2 3153 3392 Script error: No such module "val". Script error: No such module "val". gpos 75
18 q 21.31 3392 3519 Script error: No such module "val". Script error: No such module "val". gneg
18 q 21.32 3519 3663 Script error: No such module "val". Script error: No such module "val". gpos 50
18 q 21.33 3663 3758 Script error: No such module "val". Script error: No such module "val". gneg
18 q 22.1 3758 4077 Script error: No such module "val". Script error: No such module "val". gpos 100
18 q 22.2 4077 4204 Script error: No such module "val". Script error: No such module "val". gneg
18 q 22.3 4204 4411 Script error: No such module "val". Script error: No such module "val". gpos 25
18 q 23 4411 4650 Script error: No such module "val". Script error: No such module "val". gneg

References

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  10. ↑ Genome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26.
  11. ↑ "p": Short arm; "q": Long arm.
  12. ↑ For cytogenetic banding nomenclature, see article locus.
  13. ↑ a b These values (ISCN start/stop) are based on the length of bands/ideograms from the ISCN book, An International System for Human Cytogenetic Nomenclature (2013). Arbitrary unit.
  14. ↑ gpos: Region which is positively stained by G banding, generally AT-rich and gene poor; gneg: Region which is negatively stained by G banding, generally CG-rich and gene rich; acen Centromere. var: Variable region; stalk: Stalk.

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External links

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