Chromosome 16
Template:Short description Template:Infobox chromosome Chromosome 16 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 16 spans about 90 million base pairs (the building material of DNA) and represents just under 3% of the total DNA in cells.
Genes
Number of genes
The following are some of the gene count estimates of human chromosome 16. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.[1]
| Estimated by | Protein-coding genes | Non-coding RNA genes | Pseudogenes | Source | Release date |
|---|---|---|---|---|---|
| CCDS | 795 | — | — | [2] | 2016-09-08 |
| HGNC | 802 | 251 | 365 | [3] | 2017-05-12 |
| Ensembl | 865 | 1,046 | 462 | [4] | 2017-03-29 |
| UniProt | 838 | — | — | [5] | 2018-02-28 |
| NCBI | 912 | 652 | 502 | [6][7][8] | 2017-05-19 |
Gene list
Script error: No such module "Category see also".Template:Category see also/Category pair check The following is a partial list of genes on human chromosome 16. For complete list, see the link in the infobox on the right. Script error: No such module "Template wrapper".Script error: No such module "Check for unknown parameters".
Diseases and disorders
- Attention deficit hyperactivity disorder (ADHD)
- Asperger syndrome
- Autism spectrum disorder[9][10]
- Autosomal dominant polycystic kidney disease (PKD-1)
- Batten disease
- Combined malonic and methylmalonic aciduria (CMAMMA)
- Familial Mediterranean fever (FMF)
- Synesthesia
- Thalassemia
- Trisomy 16
- Morquio syndrome
Associated traits
Cytogenetic band
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| Chr. | Arm[12] | Band[13] | ISCN start[14] |
ISCN stop[14] |
Basepair start |
Basepair stop |
Stain[15] | Density |
|---|---|---|---|---|---|---|---|---|
| 16 | p | 13.3 | 0 | 352 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | p | 13.2 | 352 | 596 | Script error: No such module "val". | Script error: No such module "val". | gpos | 50 |
| 16 | p | 13.13 | 596 | 813 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | p | 13.12 | 813 | 948 | Script error: No such module "val". | Script error: No such module "val". | gpos | 50 |
| 16 | p | 13.11 | 948 | 1070 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | p | 12.3 | 1070 | 1246 | Script error: No such module "val". | Script error: No such module "val". | gpos | 50 |
| 16 | p | 12.2 | 1246 | 1409 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | p | 12.1 | 1409 | 1558 | Script error: No such module "val". | Script error: No such module "val". | gpos | 50 |
| 16 | p | 11.2 | 1558 | 1856 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | p | 11.1 | 1856 | 2045 | Script error: No such module "val". | Script error: No such module "val". | acen | |
| 16 | q | 11.1 | 2045 | 2194 | Script error: No such module "val". | Script error: No such module "val". | acen | |
| 16 | q | 11.2 | 2194 | 2709 | Script error: No such module "val". | Script error: No such module "val". | gvar | |
| 16 | q | 12.1 | 2709 | 2953 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | q | 12.2 | 2953 | 3142 | Script error: No such module "val". | Script error: No such module "val". | gpos | 50 |
| 16 | q | 13 | 3142 | 3346 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | q | 21 | 3346 | 3657 | Script error: No such module "val". | Script error: No such module "val". | gpos | 100 |
| 16 | q | 22.1 | 3657 | 4023 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | q | 22.2 | 4023 | 4118 | Script error: No such module "val". | Script error: No such module "val". | gpos | 50 |
| 16 | q | 22.3 | 4118 | 4294 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | q | 23.1 | 4294 | 4551 | Script error: No such module "val". | Script error: No such module "val". | gpos | 75 |
| 16 | q | 23.2 | 4551 | 4659 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | q | 23.3 | 4659 | 4768 | Script error: No such module "val". | Script error: No such module "val". | gpos | 50 |
| 16 | q | 24.1 | 4768 | 4930 | Script error: No such module "val". | Script error: No such module "val". | gneg | |
| 16 | q | 24.2 | 4930 | 5025 | Script error: No such module "val". | Script error: No such module "val". | gpos | 25 |
| 16 | q | 24.3 | 5025 | 5120 | Script error: No such module "val". | Script error: No such module "val". | gneg |
References
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- ↑ Genome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26.
- ↑ "p": Short arm; "q": Long arm.
- ↑ For cytogenetic banding nomenclature, see article locus.
- ↑ a b These values (ISCN start/stop) are based on the length of bands/ideograms from the ISCN book, An International System for Human Cytogenetic Nomenclature (2013). Arbitrary unit.
- ↑ gpos: Region which is positively stained by G banding, generally AT-rich and gene poor; gneg: Region which is negatively stained by G banding, generally CG-rich and gene rich; acen Centromere. var: Variable region; stalk: Stalk.
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- http://omim.org/search?index=geneMap&search=16p13.3
External links
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