Chris Abell

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Template:Short description Template:EngvarB Script error: No such module "Unsubst". Script error: No such module "Template wrapper".Script error: No such module "Check for clobbered parameters". Christopher Abell (11 November 1957[1] – 26 October 2020[2]) was a British biological chemist who was a professor of biological chemistry at the Yusuf Hamied Department of Chemistry and Todd-Hamied Fellow of Christ's College, Cambridge.[3] On his 2016 election to the Royal Society, Abell's research was described as having "changed the face of drug discovery."[4]

Education

Abell was educated at St John's College, Cambridge,[1] gaining a Bachelor of Arts degree in Natural Sciences in 1979 followed by PhD[5] on the topic of polyketide biosynthesis for research supervised by James Staunton in 1982.[6]

Career and research

Abell held a research fellowship in the laboratory of David E. Cane at Brown University, Providence, USA, studying terpene biosynthesis (1982–83).[1][6] In 1984, Abell joined the department of chemistry of the University of Cambridge, successively holding the positions of demonstrator, lecturer and reader in chemical biology, and becoming professor in biological chemistry in 2002.[1][6] He held visiting professorships at the Australian National University in Canberra, University of Santiago de Compostela, University of Canterbury, Christchurch, and the Paul Sabatier University, Toulouse.[1][6][7] He was a fellow of Christ's College, Cambridge, from 1986;[8] and was the college's Todd-Hamied Fellow.[9] In 2013 he was appointed the first director of postdoctoral affairs at the University of Cambridge,[10] and in 2016 was appointed pro-vice-chancellor for research.

Abell published over 200 papers.[1] His research interests include vitamin and amino acid biosynthesis as targets for the rational design of antimicrobials; fragment-based approaches to enzyme inhibition; bacterial and plant riboswitches; reactions in microdroplets;[11] and biological nanotechnology.[12] His former doctoral students include Shankar Balasubramanian.[13]

Commercial ventures

Abell was the co-founder of several companies. In 1999, he co-founded Astex Technology Ltd, which uses fragment-based drug discovery technology to discover cancer therapeutics.[1][7] In 2001, he co-founded Akubio, which developed biosensors for detecting bacteria and viruses; it was acquired by Inverness Medical Innovations in 2008.[14] In 2010, he co-founded Sphere Fluidics to develop microdroplet technology.[15] In 2012 he co-founded Aqdot, a company developing a new microencapsulation technology.[16]

Personal life

In 1981, he married Katherine Abell, who worked with him at the department of chemistry in Cambridge; they had a son.[2][6][17] He died suddenly on 26 October 2020.[2]

Awards and honours

His awards include the Imperial Chemical Industries (ICI) Prize in Organic Chemistry in 1992,[6] the Hickinbottom Award of the Royal Society of Chemistry,[18] and a Yamada Science Foundation Award.[1][6] In 2008 he was the MIT Novartis Lecturer, and in 2011 was a BIC International Fellow at the University of Canterbury, Christchurch, New Zealand.[19] He was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2012[20] and a Fellow of the Royal Society (FRS) in 2016.[21]

Selected publications

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  • From Microdroplets to Microfluidics: Selective Emulsion Separation in Microfluidic Devices[11]
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References

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  1. ↑ a b c d e f g h Abell, Prof Christopher. In Debrett's People of Today 2012 (accessed 15 January 2012) (subscription required)
  2. ↑ a b c Script error: No such module "citation/CS1".
  3. ↑ Script error: No such module "citation/CS1".
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  6. ↑ a b c d e f g Script error: No such module "citation/CS1". (accessed 15 January 2013)
  7. ↑ a b Astex Therapeutics: Scientific Advisors and Clinical Consultants Script error: No such module "webarchive". (accessed 5 January 2009)
  8. ↑ Script error: No such module "citation/CS1".
  9. ↑ Christ's College, University of Cambridge: The Fellows of Christ's College Script error: No such module "webarchive". (accessed 7 January 2013)
  10. ↑ University of Cambridge: new senior post to support post-doc community (accessed 28 November 2013)
  11. ↑ a b Script error: No such module "Citation/CS1".
  12. ↑ University of Cambridge: Department of Chemistry: Professor Chris Abell (accessed 5 January 2009)
  13. ↑ Cite error: Script error: No such module "Namespace detect".Script error: No such module "Namespace detect".
  14. ↑ Vargas L. Recycled Cambridge biosensor technology attracts millions in investment Business Weekly (27 August 2008) (accessed 5 January 2009)
  15. ↑ Sphere Fluidics: 2010 News Script error: No such module "webarchive". (accessed 7 January 2013)
  16. ↑ Script error: No such module "citation/CS1".
  17. ↑ Script error: No such module "citation/CS1".
  18. ↑ Script error: No such module "citation/CS1".
  19. ↑ International Fellows Script error: No such module "webarchive"., University of Canterbury – Christchurch. Retrieved 3 December 2013
  20. ↑ The Academy of Medical Sciences: Fellows: Newly elected fellows Script error: No such module "webarchive". (accessed 7 January 2013)
  21. ↑ Script error: No such module "citation/CS1".

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