Chlordecone reductase
Template:Short description Template:Infobox enzyme In enzymology, a chlordecone reductase (EC 1.1.1.225) is an enzyme that catalyzes the chemical reaction
- chlordecone alcohol + NADP+ chlordecone + NADPH + H+
Thus, the two substrates of this enzyme are chlordecone alcohol and NADP+, whereas its 3 products are chlordecone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is chlordecone-alcohol:NADP+ 2-oxidoreductase. This enzyme is also called CDR.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2FVL.
References
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