Carboxylesterase 2
Template:Short description Script error: No such module "redirect hatnote". Template:Infobox gene Carboxylesterase 2 is an enzyme that in humans is encoded by the CES2 gene.[1][2][3] It is a member of the alpha/beta fold hydrolase family.[4]
Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolyze long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood–brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[3]
Interactive pathway map
Template:FluoropyrimidineActivity WP1601 Template:IrinotecanPathway WP229
References
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Further reading
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