Carbapenam

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Carbapenam
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A carbapenam is the parent member of the β-lactams compounds. The parent is of only of theoretical interest, but substituted derivatives are important carbapenem antibiotics, originally inspired by the structure of penicillin. In penicillin, the five-membered ring contains sulfur, whereas carbapenams have a CH2 in place of S. A related class of antibiotics are unsaturated carbapenems.[1] Carbapenam-based antibiotics are widely used, but resistant strains of some pathogens have emerged.[2]

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Structure of (3S,5R)-carbapenam-3-carboxylic acid

References

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