Carbadox
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| Appearance | Yellow crystals |
| Density | 1.44 g/cm3 |
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Carbadox is a veterinary drug that combats infection in swine, particularly swine dysentery.
Indications
Carbadox is indicated for control of swine dysentery (vibrionic dysentery, bloody scours, or hemorrhagic dysentery); control of bacterial swine enteritis (salmonellosis or necrotic enteritis caused by Salmonella enterica); aid in the prevention of migration and establishment of large roundworm (Ascaris suum) infections; aid in the prevention of establishment of nodular worm (Oesophagostomum) infections.[1]
Safety
In animal models, carbadox has been shown to be carcinogenicScript error: No such module "Unsubst". and to induce birth defects.[2] The Food and Drug Administration's Center for Veterinary Medicine has questioned the safety in light of its possible carcinogenicity.[3]
Regulation
Carbadox is approved in the United States only for use in swine and may not be used within 42 days of slaughter or used in pregnant animals.[1] In 2016, the United States Food and Drug Administration moved to ban its use in pork, citing a potential cancer risk to humans.[4] However, as of August 2018, FDA had indefinitely stayed its withdrawal of approval and carbadox remains available. [5]
In 2004, carbadox was banned by the Canadian government as a livestock feed additive and for human consumption.[6]Script error: No such module "Unsubst". The European Union also forbids the use of carbadox at any level.[7] Australia forbids the use of carbadox in food producing animals.[8]
References
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