CSTF2

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Template:Short description Template:Infobox gene Cleavage stimulation factor 64 kDa subunit is a protein that in humans is encoded by the CSTF2 gene.[1][2]

This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.[2]

Interactions

CSTF2 has been shown to interact with CSTF3,[3] SUB1,[4] SYMPK,[3] BARD1[5][6] and BRCA1.[5][6]

References

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External links

Further reading

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