CASP8AP2
Template:Cs1 config Template:Short description Template:Infobox gene CASP8-associated protein 2 is a protein, that in humans is encoded by the CASP8AP2 gene.[1][2][3][4]
Function
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Researches of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex, that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis.[4]
Interactions
CASP8AP2 has been shown to interact with TRAF2.[5]
References
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Further reading
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