C3a receptor
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The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor protein involved in the complement system.[1][2]
The receptor binds to complement component C3a, although there is limited evidence that this receptor also binds C4a in lesser mammals. This has yet to be proven true in humans.[3] C3a receptor modulates immunity,[4] arthritis, diet-induced obesity[5] and cancers.[6]
Agonists and antagonists
Potent and selective agonists[7] and antagonists[8] for C3aR have been discovered.
References
Further reading
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External links
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