Blue nevus
Template:Short description Template:Infobox medical condition (new) A blue nevus is a type of coloured mole, typically a single well-defined blue-black bump.[1][2]
The blue colour is caused by the pigment being deep in the skin.[3]
Diagnosis is by visualisation and dermoscopy.[3] A biopsy is sometimes performed, or the whole lesion surgically removed.[4] The outcome is generally good but there is a small chance of cancerous transformation.[4] Differential diagnosis includes dermatofibroma and melanoma.[4]
Blue nevi are more common in females than males.[2] It was first studied in 1906 by Tièche, a student of Josef Jadassohn.[5]
Classification
Blue nevi may be divided into the following types:[6]Template:Rp
- A patch blue nevus (also known as an "acquired dermal melanocytosis", and "dermal melanocyte hamartoma") is a cutaneous condition characterized by a diffusely gray-blue area that may have superimposed darker macules.[1]
- A blue nevus of Jadassohn–Tièche (also known as a "common blue nevus", and "nevus ceruleus") is a cutaneous condition characterized by a steel-blue papule or nodule.[6]Template:Rp
- A cellular blue nevus is a cutaneous condition characterized by large, firm, blue or blue-black nodules.[6]Template:Rp
- An epithelioid blue nevus is a cutaneous condition most commonly seen in patients with the Carney complex.[6]Template:Rp
- A deep penetrating nevus is a type of benign melanocytic skin tumor characterized, as its name suggests, by penetration into the deep dermis and/or subcutis. Smudged chromatic is a typical finding. In some cases mitotic figures or atypical melanocytic cytology are seen, potentially mimicking a malignant melanoma. Evaluation by an expert skin pathologist is advisable in some cases to help differentiate from invasive melanoma.[6]Template:Rp
- An amelanotic blue nevus (also known as a "hypomelanotic blue nevus") is a cutaneous condition characterized by mild atypia and pleomorphism.[6]Template:Rp
- A malignant blue nevus is a cutaneous condition characterized by a sheet-like growth pattern, mitoses, necrosis, and cellular atypia.[1][6]Template:Rp
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Micrograph of a blue nevus showing the characteristic pigmented melanocytes between bundles of collagen. H&E stain
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Blue nevus
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Cellular blue nevus
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Epithelioid blue nevus
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Malignant blue nevus
See also
References
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External links
Template:Medical resources Template:Skin tumors, nevi and melanomas