Bitolterol
Template:Short description Template:Drugbox
Bitolterol mesylate, formerly sold under the brand name Tornalate, is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma[1][2] and chronic obstructive pulmonary disease (COPD).[3][4][5] Bitolterol relaxes the smooth muscles present continuously around the bronchi and bronchioles facilitating the flow of air through them.
Bitolterol is a prodrug of colterol.[6][7] It has a rapid onset of action (2–5 minutes) and may last up to 6–8 hours.[8] The drug, alone or in co-administration with theophylline, doesn't show cardiotoxic effect.[9]
The US Food and Drug Administration (FDA) approved bitolterol in December 1984. The drug was withdrawn from the market by Élan Pharmaceuticals in 2001.
References
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