Benzoin aldolase

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The enzyme benzoin aldolase (Template:EnzExplorer) catalyzes the chemical reaction:

2-hydroxy-1,2-diphenylethanone[1] 2 benzaldehyde

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of benzoin is indeed is 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)—the systematic name of benzoin is 2-hydroxy-1,2-diphenylethanone. Other names in common use include benzaldehyde lyase, and 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase. This enzyme employs one cofactor: thiamin diphosphate.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 2AG0, 2AG1, and 2UZ1.

References

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  1. Also known as benzoin.

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