Bay K8644
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| Solubility in other solvents | DMSO: 184 mg/mL; methanol and ethanol: 63 mg/mL |
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Bay K8644 is a chemical compound that functions as an L-type calcium channel agonist. Bay K8644 is used primarily as a biochemical research tool for this effect.[2] It is a structural analog of nifedipine with positive inotropic activity, and as an aromatic it is highly lipid soluble.
Mechanism of action
Bay K8644 targets L-type voltage-gated calcium channels. It is the first positive inotropic agent shown to act specifically and directly on calcium channels.[3]
References
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- ↑ (±)-Bay K8644 at Sigma-Aldrich
- ↑ CID 2303 from PubChemTemplate:EditAtWikidataTemplate:WikidataCheck
- ↑ Script error: No such module "Citation/CS1".
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