BBS10

Template:Short description Template:Infobox gene Bardet–Biedl syndrome 10, also known as BBS10 is a human gene.

Function

The Bardet-Biedl syndrome 10 protein has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes.

Clinical significance

Mutations in this gene are associated with the Bardet–Biedl syndrome.

External links

• GeneReviews/NIH/NCBI/UW entry on Bardet-Biedl Syndrome
• Template:Replace at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• Template:UCSC gene info

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