Androgen-dependent condition
Template:Infobox medical condition An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body.Script error: No such module "Unsubst".
Known androgen-dependent conditions include acne,[1] seborrhea,[2][3][4] androgenic alopecia,[5] hirsutism,[6] hidradenitis suppurativa,[7] precocious puberty in boys,[8] hypersexuality,[9] paraphilias,[10] benign prostatic hyperplasia (BPH),[11] prostate cancer,[12] and hyperandrogenism in women such as in polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia (CAH), and androgen-secreting tumors (gonadal or adrenal tumor).[13][14]
Such conditions may be treated with drugs with antiandrogen actions, including androgen receptor antagonists such as cyproterone acetate, spironolactone, and bicalutamide, 5α-reductase inhibitors such as finasteride and dutasteride, CYP17A1 inhibitors such as abiraterone acetate, gonadotropin-releasing hormone (GnRH) analogues such as leuprorelin and cetrorelix, and/or other antigonadotropins such as megestrol acetate and medroxyprogesterone acetate.[15][16]
See also
- Androgen deprivation therapy
- Androgen insensitivity syndrome
- Estrogen-dependent condition
- Spinal bulbar muscular atrophy
References
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Further reading
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