Aminopenicillin

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File:Aminopenicillin.svg
Generalized structure of aminopenicillins
File:Ampicillin structure.svg
ampicillin

The aminopenicillins are a group of antibiotics in the penicillin family that are structural analogs of ampicillin (which is the 2-amino derivative of benzylpenicillin, hence the name).[1] Like other penicillins and beta-lactam antibiotics, they contain a beta-lactam ring that is crucial to its antibacterial activity.Script error: No such module "Unsubst".

Aminopenicillins feature a positively charged amino group that enhances their uptake through bacterial porin channels. This does not, however, prevent resistance conferred by bacterial beta-lactamases.[2] Members of this family include ampicillin, amoxicillin and bacampicillin.[3]

See also

References

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