Agmatinase
Template:Short description Template:Infobox enzyme In enzymology, an agmatinase (EC 3.5.3.11) is an enzyme that catalyzes the chemical reaction
- agmatine + H2O putrescine + urea
Thus, the two substrates of this enzyme are agmatine and H2O, whereas its two products are putrescine and urea.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is agmatine amidinohydrolase. Other names in common use include agmatine ureohydrolase. This enzyme participates in urea cycle and metabolism of amino groups.
Genetics
Template:Infobox gene In humans, the enzyme is encoded by the AGMAT gene.[1][2][3][4]
Structural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 1GQ6, 1GQ7, 1WOG, 1WOH, and 1WOI.
Inhibitors
References
<templatestyles src="Reflist/styles.css" />
Script error: No such module "Check for unknown parameters".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Template:MeshName
External links
Script error: No such module "Navbox". Script error: No such module "Navbox". Script error: No such module "Navbox". Template:Portal bar