ATP2A2

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

Template:Short descriptionTemplate:Infobox gene

ATP2A2 also known as sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) is an ATPase associated with Darier's disease[1] and Acrokeratosis verruciformis.

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells.[2] This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.

References

<templatestyles src="Reflist/styles.css" />

Script error: No such module "Check for unknown parameters".

External links

Template:Asbox Script error: No such module "Navbox".