ASF1A

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Template:Short description Template:Cs1 config Template:Infobox gene Histone chaperone ASF1A is a protein that in humans is encoded by the ASF1A gene.[1][2][3]

Function

This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The protein is a key component of a histone donor complex that functions in nucleosome assembly. It interacts with histones H3 and H4, and functions together with a chromatin assembly factor during DNA replication and repair.[3]

Interactions

ASF1A has been shown to interact with TLK1,[4][5] TLK2,[4] CHAF1B[6] and CHAF1A.[6]

References

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Further reading

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External links

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