AM-905
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Template:Short description Template:Drugbox
AM-905 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid agonist. It is conformationally restricted by virtue of the double bond on its side chain, leading an increased affinity for and selectivity between CB1 and CB2 receptors.[1] It is a potent and reasonably selective agonist for the CB1 cannabinoid receptor, with a Ki of 1.2 nM at CB1 and 5.3 nM at CB2.[2]
See also
- 1,2-Didehydro-3-oxo-THCO
- AM-906 - The corresponding Z or cis isomer
- HU-243 - Double bond replaced by geminal methyls for Thorpe–Ingold effect
References
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