AKAP1

Template:Short description Template:Infobox gene A kinase anchor protein 1, mitochondrial is an enzyme that in humans is encoded by the AKAP1 gene.

Function

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins that have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.

Interactions

AKAP1 has been shown to interact with:

• C3orf15,
• MYCBP,
• PRKAR1A,
• PRKAR1B, and
• PRKAR2A.

External links

• Template:UCSC gene info

Further reading

Template:Asbox