ADAM2
Template:Short description Script error: No such module "Unsubst". Template:Infobox gene Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin[1] is an enzyme that in humans is encoded by the ADAM2 gene.[2][3][4]
Function
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell–cell and cell–matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane heterodimer glycoprotein called fertilin, which plays an important role in sperm-egg interactions.[4] The other subunit is ADAM1 or alpha-fertilin.[1]
References
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Further reading
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External links
- The MEROPS online database for peptidases and their inhibitors: M12.950
- Template:UCSC gene info
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