7-ACA

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7-Aminocephalosporanic acid
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Abbreviations 7-ACA
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MeSH 7-Aminocephalosporanic+acid
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log P −1.87
Acidity (pKa) 2.59
Basicity (pKb) 11.41

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7-ACA (7-aminocephalosporanic acid) is the core chemical structure (a synthon) for the synthesis of cephalosporin antibiotics and intermediates. It can be obtained by chemoenzymatic hydrolysis of cephalosporin C.[1][2]

The production of 7-ACA (7-aminocephalosporanic acid) is predominantly segmented into two methods which is Enzymatic Hydrolysis and Chemical Cracking. These processes are essential for the synthesis of various cephalosporin antibiotics.[3]

See also

References

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