Imidazol-4-one-5-propionic acid
(Redirected from 4-imidazolone-5-propionic acid)
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| MeSH | Imidazol-4-one-5-propionic+acid |
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| Template:Longitem | C6H8N2O3 |
| Molar mass | 156.139 |
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Imidazol-4-one-5-propionic acid is an intermediate in the metabolism of histidine. It is a colorless compound that is sensitive to light in air. The compound features an imidazolone ring.[1]
Occurrence
It arises via the action of urocanase on urocanic acid. Hydrolysis of the heterocycle to the glutamic acid derivative is catalyzed by imidazolonepropionate hydrolase.
Microbial production of imidazol-4-one-5-propionic acid in the human gut has been shown to affect insulin signaling, which is relevant to type II diabetes.[2]
See also
References
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