3C-E
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3C-E, also known as 4-ethoxy-3,5-dimethoxyamphetamine or as α-methylescaline (3C-escaline), is a psychedelic drug of the phenethylamine, amphetamine, and 3C families related to 3,4,5-trimethoxyamphetamine (TMA).[1][2][3] It is the amphetamine (3C) analogue of escaline.[1][3] The drug has a dose range of 30 to 60Script error: No such module "String".mg orally, with a typical dose estimate of 45Script error: No such module "String".mg, and a duration of 8 to 12Script error: No such module "String".hours.[1][4][2][3][5] It has about the same potency as escaline.[1][4][6] The drug is a potent serotonin 5-HT2A receptor agonist and also interacts with other serotonin receptors and targets.[3][2] It produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents.[7][5] 3C-E was first described in the scientific literature by Benington and colleagues in 1954.[8] Alexander Shulgin and colleagues reported an active dose of 40Script error: No such module "String".mg based on unpublished findings in a 1978 literature review.[9][10] Subsequently, Shulgin further reported the properties and effects of 3C-E in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).[1] The drug was encountered as a novel designer drug in Europe in 2013.[11][12][7]
See also
References
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- ↑ a b c d e PiHKAL entry
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External links
- 3C-E - Isomer Design
- 3C-E - PsychonautWiki
- 3C-E - PiHKAL - Erowid
- 3C-E - PiHKAL - Isomer Design
- The Small & Handy 3C-E Thread - Bluelight
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