2-oxoadipate reductase

Template:Short description Template:Infobox enzyme In enzymology, a 2-oxoadipate reductase (EC 1.1.1.172) is an enzyme that catalyzes the chemical reaction

2-hydroxyadipate + NAD⁺ $\rightleftharpoons$ 2-oxoadipate + NADH + H⁺

Thus, the two substrates of this enzyme are 2-hydroxyadipate and NAD⁺, whereas its 3 products are 2-oxoadipate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 2-hydroxyadipate:NAD⁺ 2-oxidoreductase. Other names in common use include 2-ketoadipate reductase, alpha-ketoadipate reductase, and 2-ketoadipate reductase.

References

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