2-Coumarate reductase

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Template:Short description Template:Infobox enzyme In enzymology, a 2-coumarate reductase or melilotate dehydrogenase (EC 1.3.1.11) is an enzyme that catalyzes the chemical reaction

3-(2-hydroxyphenyl)propanoate + NAD+ 2-coumarate + NADH + H+

Thus, the two substrates of this enzyme are 3-(2-hydroxyphenyl)propanoate and NAD+, whereas its 3 products are 2-coumarate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase. This enzyme participates in phenylalanine metabolism.

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