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{{short description|Unpleasant experience triggered by psychoactive drugs}}
{{short description|Unpleasant experience triggered by psychoactive drugs}}
{{Other uses|Bad Trip (disambiguation){{!}}Bad Trip}}
{{Other uses|Bad Trip (disambiguation){{!}}Bad Trip}}
{{Psychedelic sidebar |expanded=Effects}}
A '''bad trip''' (also known as '''challenging experiences''', '''acute intoxication from hallucinogens''', '''psychedelic crisis''', or '''emergence phenomenon''') is an acute adverse psychological reaction to the effects of [[Psychoactive drug|psychoactive substances]], namely [[psychedelics]]. There is no clear definition of what constitutes a bad trip. Additionally, knowledge on the cause of bad trips and who may be vulnerable to such experiences are limited. Existing studies report that possible adverse reactions include [[anxiety]], panic, [[depersonalization]], [[Ego death|ego dissolution]], [[paranoia]], as well as physiological symptoms such as dizziness and [[Palpitations|heart palpitations]]. However, most studies indicate that the ''[[set and setting]]'' of substance use influence how people respond.<ref>{{Cite journal |last1=Gashi |first1=Liridona |last2=Sandberg |first2=Sveinung |last3=Pedersen |first3=Willy |date=2021 |title=Making "bad trips" good: How users of psychedelics narratively transform challenging trips into valuable experiences |journal=International Journal of Drug Policy |volume=87 |article-number=102997 |doi=10.1016/j.drugpo.2020.102997 |pmid=33080454 |issn=0955-3959|hdl=10852/81144 |hdl-access=free }}</ref>
A '''bad trip''' (also known as '''challenging experiences''', '''acute intoxication from hallucinogens''', '''psychedelic crisis''', or '''emergence phenomenon''') is an acute adverse psychological reaction to the effects of [[Psychoactive drug|psychoactive substances]], namely [[psychedelics]]. There is no clear definition of what constitutes a bad trip. Additionally, knowledge on the cause of bad trips and who may be vulnerable to such experiences are limited. Existing studies report that possible adverse reactions include [[anxiety]], panic, [[depersonalization]], [[Ego death|ego dissolution]], [[paranoia]], as well as physiological symptoms such as dizziness and [[Palpitations|heart palpitations]]. However, most studies indicate that the ''[[set and setting]]'' of substance use influence how people respond.<ref>{{Cite journal |last1=Gashi |first1=Liridona |last2=Sandberg |first2=Sveinung |last3=Pedersen |first3=Willy |date=2021 |title=Making "bad trips" good: How users of psychedelics narratively transform challenging trips into valuable experiences |url=https://doi.org/10.1016/j.drugpo.2020.102997 |journal=International Journal of Drug Policy |volume=87 |pages=102997 |doi=10.1016/j.drugpo.2020.102997 |pmid=33080454 |issn=0955-3959|hdl=10852/81144 |hdl-access=free }}</ref>


Bad trips can be exacerbated by the inexperience or irresponsibility of the user or the lack of [[Set and setting|proper preparation and environment for the trip]], and are often reflective of unresolved psychological tensions triggered during the course of the experience.<ref name="grof-lsd-pt">{{Cite book |last=Grof |first=Stanislav |url=https://books.google.com/books?id=jAvSPgAACAAJ |title=LSD Psychotherapy |date=2008 |publisher=Multidisciplinary Association for Psychedelic Studies |isbn=978-0-9798622-0-5 |language=en}}</ref>{{page needed|date=October 2020}} In clinical research settings, precautions including the screening and preparation of participants, the training of the session monitors who will be present during the experience, and the selection of appropriate physical setting can minimize the likelihood of psychological distress.<ref name="johnson-et-al-2008">{{Cite journal |last1=Johnson |first1=Matthew W. |last2=Richards |first2=William A. |last3=Griffiths |first3=Roland R. |date=2008 |title=Human Hallucinogen Research: Guidelines for Safety |journal=Journal of Psychopharmacology |volume=22 |issue=6 |pages=603–620 |doi=10.1177/0269881108093587 |pmc=3056407 |pmid=18593734}}</ref> Researchers have suggested that the presence of professional "[[trip sitter]]s" (i.e., session monitors) may significantly reduce the negative experiences associated with a bad trip.<ref name="gashi-et-al-2021">{{Cite journal |last1=Gashi |first1=Liridona |last2=Sandberg |first2=Sveinung |last3=Pederson |first3=Willy |date=2021 |title=Making "bad trips" good: How users of psychedelics narratively transform challenging trips into valuable experiences |journal=International Journal of Drug Policy |volume=87 |pages=102997 |doi=10.1016/j.drugpo.2020.102997 |pmid=33080454 |hdl-access=free |hdl=10852/81144|s2cid=224821288 }}</ref> In most cases in which anxiety arises during a supervised psychedelic experience, reassurance from the session monitor is adequate to resolve it; however, if distress becomes intense it can be treated pharmacologically, for example with the [[benzodiazepine]] [[diazepam]].<ref name="johnson-et-al-2008" />
Bad trips can be exacerbated by the inexperience or irresponsibility of the user or the lack of [[Set and setting|proper preparation and environment for the trip]], and are often reflective of unresolved psychological tensions triggered during the course of the experience.<ref name="grof-lsd-pt">{{Cite book |last=Grof |first=Stanislav |url=https://books.google.com/books?id=jAvSPgAACAAJ |title=LSD Psychotherapy |date=2008 |publisher=Multidisciplinary Association for Psychedelic Studies |isbn=978-0-9798622-0-5 |language=en}}</ref>{{page needed|date=October 2020}} In clinical research settings, precautions including the screening and preparation of participants, the training of the session monitors who will be present during the experience, and the selection of appropriate physical setting can minimize the likelihood of psychological distress.<ref name="johnson-et-al-2008">{{Cite journal |last1=Johnson |first1=Matthew W. |last2=Richards |first2=William A. |last3=Griffiths |first3=Roland R. |date=2008 |title=Human Hallucinogen Research: Guidelines for Safety |journal=Journal of Psychopharmacology |volume=22 |issue=6 |pages=603–620 |doi=10.1177/0269881108093587 |pmc=3056407 |pmid=18593734}}</ref> Researchers have suggested that the presence of professional "[[trip sitter]]s" (i.e., session monitors) may significantly reduce the negative experiences associated with a bad trip.<ref name="gashi-et-al-2021">{{Cite journal |last1=Gashi |first1=Liridona |last2=Sandberg |first2=Sveinung |last3=Pederson |first3=Willy |date=2021 |title=Making "bad trips" good: How users of psychedelics narratively transform challenging trips into valuable experiences |journal=International Journal of Drug Policy |volume=87 |article-number=102997 |doi=10.1016/j.drugpo.2020.102997 |pmid=33080454 |hdl-access=free |hdl=10852/81144|s2cid=224821288 }}</ref> In most cases in which anxiety arises during a supervised psychedelic experience, reassurance from the session monitor is adequate to resolve it; however, if distress becomes intense it can be treated pharmacologically, for example with the [[benzodiazepine]] [[diazepam]].<ref name="johnson-et-al-2008" />


The psychiatrist [[Stanislav Grof]] wrote that unpleasant psychedelic experiences are not necessarily unhealthy or undesirable, arguing that they may have the potential for psychological healing and lead to breakthrough and resolution of unresolved psychic issues.<ref name="grof-lsd-pt" />{{page needed|date=October 2020}} Drawing on [[narrative theory]], the authors of a 2021 study of 50 users of psychedelics found that many described bad trips as having been sources of insight or even turning points in life.<ref name="gashi-et-al-2021" />
The psychiatrist [[Stanislav Grof]] wrote that unpleasant psychedelic experiences are not necessarily unhealthy or undesirable, arguing that they may have the potential for psychological healing and lead to breakthrough and resolution of unresolved psychic issues.<ref name="grof-lsd-pt" />{{page needed|date=October 2020}} Drawing on [[narrative theory]], the authors of a 2021 study of 50 users of psychedelics found that many described bad trips as having been sources of insight or even turning points in life.<ref name="gashi-et-al-2021" />
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== Signs and symptoms ==
== Signs and symptoms ==
{{See also|Psychosis|Substance-induced psychosis}}
{{See also|Psychosis|Substance-induced psychosis}}
With proper screening, preparation, and support in a regulated setting these are usually benign.<ref>{{cite journal |last1=Barrett |first1=FS |last2=Bradstreet |first2=MP |last3=Leoutsakos |first3=JS |last4=Johnson |first4=MW |last5=Griffiths |first5=RR |date=December 2016 |title=The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms. |journal=Journal of Psychopharmacology |volume=30 |issue=12 |pages=1279–1295 |doi=10.1177/0269881116678781 |pmc=5549781 |pmid=27856683}}</ref> A bad trip on [[psilocybin]], for instance, often features intense anxiety, confusion, agitation, and [[psychosis]].<ref name="van-amsterdam-et-al">{{Cite journal |last1=van Amsterdam |first1=Jan |last2=Opperhuizen |first2=Antoon |last3=van den Brink |first3=Wim |date=2011 |title=Harm potential of magic mushroom use: A review |journal=Regulatory Toxicology and Pharmacology |volume=59 |issue=3 |pages=423–429 |doi=10.1016/j.yrtph.2011.01.006 |pmid=21256914}}</ref> They manifest as a range of feelings, such as anxiety, paranoia, the unshakeable sense of one's inevitable and imminent personal demise or states of unrelieved terror that they believe will persist after the substance's [[Pharmacokinetics#LADME|effects]] have worn off. As of 2011, exact data on the frequency of bad trips are not available.<ref name="van-amsterdam-et-al" />
With proper screening, preparation, and support in a regulated setting symptoms are usually benign.<ref>{{cite journal |last1=Barrett |first1=FS |last2=Bradstreet |first2=MP |last3=Leoutsakos |first3=JS |last4=Johnson |first4=MW |last5=Griffiths |first5=RR |date=December 2016 |title=The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms. |journal=Journal of Psychopharmacology |volume=30 |issue=12 |pages=1279–1295 |doi=10.1177/0269881116678781 |pmc=5549781 |pmid=27856683}}</ref> A bad trip on [[psilocybin]], for instance, often features intense anxiety, confusion, agitation, and [[psychosis]].<ref name="van-amsterdam-et-al">{{Cite journal |last1=van Amsterdam |first1=Jan |last2=Opperhuizen |first2=Antoon |last3=van den Brink |first3=Wim |date=2011 |title=Harm potential of magic mushroom use: A review |journal=Regulatory Toxicology and Pharmacology |volume=59 |issue=3 |pages=423–429 |doi=10.1016/j.yrtph.2011.01.006 |pmid=21256914}}</ref> They manifest as a range of feelings, such as anxiety, paranoia, the unshakeable sense of one's inevitable and imminent personal demise or states of unrelieved terror that they believe will persist after the substance's [[Pharmacokinetics#LADME|effects]] have worn off. As of 2011, exact data on the frequency of bad trips are not available.<ref name="van-amsterdam-et-al" />


== Treatment ==<!-- Treatment (i.e., management, intervention) -->
== Treatment ==<!-- Treatment (i.e., management, intervention) -->
{{See also|Trip killer}}
[[File:Xanax (alprazolam) 2 mg.jpg|thumb|[[Alprazolam|Xanax]] is an [[benzodiazepine]] used as a [[trip killer]].]]
Medical treatment consists of supportive therapy and minimization of external stimuli. In some cases, [[sedation]] is used when necessary to control self-destructive behavior, or when [[hyperthermia]] occurs. A [[trip killer]] such as [[alprazolam]], [[diazepam]], [[quetiapine]], or [[trazodone]] is the most frequently used treatment.<ref>{{Cite journal |last=Yates |first=Gregory |last2=Melon |first2=Emily |date=2024-02-01 |title=Trip-killers: a concerning practice associated with psychedelic drug use |url=https://emj.bmj.com/content/41/2/112 |journal=Emergency Medicine Journal |language=en |volume=41 |issue=2 |pages=112–113 |doi=10.1136/emermed-2023-213377 |issn=1472-0205 |pmid=38123961}}</ref> Other [[benzodiazepines]] such as [[lorazepam]] are also effective. Such sedatives will only decrease fear and anxiety, but will not subdue hallucinations. [[Antipsychotics]] such as [[quetiapine]], [[aripiprazole]], [[risperidone]], and [[haloperidol]] can reduce or stop hallucinations. Haloperidol is effective against acute intoxication caused by LSD and other [[tryptamine]]s, [[amphetamine]]s, [[ketamine]], and [[phencyclidine]].<ref>{{Cite journal |last1=Giannini |first1=A. James |last2=Underwood |first2=Ned A. |last3=Condon |first3=Maggie |year=2000 |title=Acute Ketamine Intoxication Treated by Haloperidol |journal=[[American Journal of Therapeutics]] |volume=7 |issue=6 |pages=389–91 |doi=10.1097/00045391-200007060-00008 |pmid=11304647}}</ref><ref>{{Cite web |title=Sage Journals |url=http://jcp.sagepub.com/cgi/pmidlookup?view=long&pmid=6725621 |archive-url=https://web.archive.org/web/20140824075401/http://online.sagepub.com/site/moved?view=long&pmid=6725621 |archive-date=2014-08-24 |access-date=2018-03-27 |language=en}} </ref>


Medical treatment consists of supportive therapy and minimization of external stimuli. In some cases, [[sedation]] is used when necessary to control self-destructive behavior, or when [[hyperthermia]] occurs. [[Diazepam]] is the most frequently used sedative for such treatment, but other [[benzodiazepines]] such as [[lorazepam]] are also effective.{{Citation needed|date=April 2020}} Such sedatives will only decrease fear and anxiety, but will not subdue hallucinations. In severe cases, antipsychotics such as [[haloperidol]] can reduce or stop hallucinations. Haloperidol is effective against acute intoxication caused by LSD and other [[tryptamine]]s, [[amphetamine]]s, [[ketamine]], and [[phencyclidine]].<ref>{{Cite journal |last1=Giannini |first1=A. James |last2=Underwood |first2=Ned A. |last3=Condon |first3=Maggie |year=2000 |title=Acute Ketamine Intoxication Treated by Haloperidol |journal=[[American Journal of Therapeutics]] |volume=7 |issue=6 |pages=389–91 |doi=10.1097/00045391-200007060-00008 |pmid=11304647}}</ref><ref>{{Cite web |title=Sage Journals |url=http://jcp.sagepub.com/cgi/pmidlookup?view=long&pmid=6725621 |archive-url=https://web.archive.org/web/20140824075401/http://online.sagepub.com/site/moved?view=long&pmid=6725621 |archive-date=2014-08-24 |access-date=2018-03-27 |language=en}} </ref>
== Pathophysiology ==
 
<!-- Signs and symptoms --><!-- Pathophysiology --><!-- Pathogenesis to be written  -->
== Pathophysiology ==<!-- Signs and symptoms --><!-- Pathophysiology --><!-- Pathogenesis to be written  -->


Bad trips may cause range of conditions such as [[psychosis]] and [[hallucinogen persisting perception disorder]] (HPPD).<ref>{{cite journal |last=Bracco |first=Jessica |date=May 2019 |title=The United States Print Media and its War on Psychedelic Research in the 1960s |url=https://digitalcommons.buffalostate.edu/exposition/vol5/iss1/2/ |journal=The Exposition |volume=5 |issue=1 |pages=9–10}}</ref>  
Bad trips may cause range of conditions such as [[psychosis]] and [[hallucinogen persisting perception disorder]] (HPPD).<ref>{{cite journal |last=Bracco |first=Jessica |date=May 2019 |title=The United States Print Media and its War on Psychedelic Research in the 1960s |url=https://digitalcommons.buffalostate.edu/exposition/vol5/iss1/2/ |journal=The Exposition |volume=5 |issue=1 |pages=9–10}}</ref>  
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Psychiatrist [[Stanislav Grof]] once said in an interview:
Psychiatrist [[Stanislav Grof]] once said in an interview:


{{blockquote|There is a tremendous danger of confusing the inner world with the outer world, so you'll be dealing with your inner realities but at the same time you are not even aware of what's happening, You perceive a sort of distortion of the world out there. So you can end up in a situation where you're weakening the resistances, your conscious is becoming more aware, but you're not really in touch with it properly, you're not really fully experiencing what's there, not seeing it for what it is. You get kind of deluded and caught into this.<ref>{{Cite web |title=Beyond Psychotic Experience - Stan Grof interviewed by Jon Atkinson |url=http://www.lycaeum.org/leda/docs/16869.shtml?ID=16869 |url-status=dead |archive-url=https://web.archive.org/web/20110927122540/http://www.lycaeum.org/leda/docs/16869.shtml?ID=16869 |archive-date=2011-09-27 |access-date=2011-04-12}}</ref>}}
{{blockquote|There is a tremendous danger of confusing the inner world with the outer world, so you'll be dealing with your inner realities but at the same time you are not even aware of what's happening, You perceive a sort of distortion of the world out there. So you can end up in a situation where you're weakening the resistances, your conscious is becoming more aware, but you're not really in touch with it properly, you're not really fully experiencing what's there, not seeing it for what it is. You get kind of deluded and caught into this.<ref>{{Cite web |title=Beyond Psychotic Experience - Stan Grof interviewed by Jon Atkinson |url=http://www.lycaeum.org/leda/docs/16869.shtml?ID=16869 |archive-url=https://web.archive.org/web/20110927122540/http://www.lycaeum.org/leda/docs/16869.shtml?ID=16869 |archive-date=2011-09-27 |access-date=2011-04-12}}</ref>}}


In a 1975 book, Grof suggested that painful and difficult experiences during a trip could be a result of the mind reliving experiences associated with birth, and that experiences of imprisonment, [[eschatological]] terror, or suffering far beyond anything imaginable in a normal state, if seen through to conclusion, often resolve into emotional, intellectual and spiritual breakthroughs. From this perspective, Grof suggests that interrupting a bad trip, while initially seen as beneficial, could potentially trap the tripper in unresolved psychological states. Grof also suggests that many cathartic experiences within psychedelic states, while not necessarily crises, may be the effects of consciousness entering a perinatal space.<ref>{{Cite book |last=Grof |first=Stanislav |title=realms of the human unconscious - Observations from LSD research |publisher=souvenir press |year=1975 |isbn=0-285-64882-9 |pages=95–153}}</ref>
In a 1975 book, Grof suggested that painful and difficult experiences during a trip could be a result of the mind reliving experiences associated with birth, and that experiences of imprisonment, [[eschatological]] terror, or suffering far beyond anything imaginable in a normal state, if seen through to conclusion, often resolve into emotional, intellectual and spiritual breakthroughs. From this perspective, Grof suggests that interrupting a bad trip, while initially seen as beneficial, could potentially trap the tripper in unresolved psychological states. Grof also suggests that many cathartic experiences within psychedelic states, while not necessarily crises, may be the effects of consciousness entering a perinatal space.<ref>{{Cite book |last=Grof |first=Stanislav |title=realms of the human unconscious - Observations from LSD research |publisher=souvenir press |year=1975 |isbn=0-285-64882-9 |pages=95–153}}</ref>
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*[[Ego death]]
*[[Ego death]]
*[[Existential crisis]]
*[[Existential crisis]]
*[[Hard and soft drugs]]
*[[Hallucinogen persisting perception disorder]]
*[[Harm reduction]]
*[[Harm reduction]]
*[[Lucid dreaming]]
*[[Near-death experience]]
*[[Near-death experience]]
*[[Out-of-body experience]]
*[[Out-of-body experience]]
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*[[Set and setting]]
*[[Set and setting]]
*[[Spiritual crisis]]
*[[Spiritual crisis]]
*[[Substance-induced psychosis]]
*[[Trip killer]]


==References==
==References==

Latest revision as of 19:01, 6 November 2025

Template:Short description Script error: No such module "other uses". A bad trip (also known as challenging experiences, acute intoxication from hallucinogens, psychedelic crisis, or emergence phenomenon) is an acute adverse psychological reaction to the effects of psychoactive substances, namely psychedelics. There is no clear definition of what constitutes a bad trip. Additionally, knowledge on the cause of bad trips and who may be vulnerable to such experiences are limited. Existing studies report that possible adverse reactions include anxiety, panic, depersonalization, ego dissolution, paranoia, as well as physiological symptoms such as dizziness and heart palpitations. However, most studies indicate that the set and setting of substance use influence how people respond.[1]

Bad trips can be exacerbated by the inexperience or irresponsibility of the user or the lack of proper preparation and environment for the trip, and are often reflective of unresolved psychological tensions triggered during the course of the experience.[2]Script error: No such module "Unsubst". In clinical research settings, precautions including the screening and preparation of participants, the training of the session monitors who will be present during the experience, and the selection of appropriate physical setting can minimize the likelihood of psychological distress.[3] Researchers have suggested that the presence of professional "trip sitters" (i.e., session monitors) may significantly reduce the negative experiences associated with a bad trip.[4] In most cases in which anxiety arises during a supervised psychedelic experience, reassurance from the session monitor is adequate to resolve it; however, if distress becomes intense it can be treated pharmacologically, for example with the benzodiazepine diazepam.[3]

The psychiatrist Stanislav Grof wrote that unpleasant psychedelic experiences are not necessarily unhealthy or undesirable, arguing that they may have the potential for psychological healing and lead to breakthrough and resolution of unresolved psychic issues.[2]Script error: No such module "Unsubst". Drawing on narrative theory, the authors of a 2021 study of 50 users of psychedelics found that many described bad trips as having been sources of insight or even turning points in life.[4]

Signs and symptoms

Script error: No such module "Labelled list hatnote". With proper screening, preparation, and support in a regulated setting symptoms are usually benign.[5] A bad trip on psilocybin, for instance, often features intense anxiety, confusion, agitation, and psychosis.[6] They manifest as a range of feelings, such as anxiety, paranoia, the unshakeable sense of one's inevitable and imminent personal demise or states of unrelieved terror that they believe will persist after the substance's effects have worn off. As of 2011, exact data on the frequency of bad trips are not available.[6]

Treatment

Script error: No such module "Labelled list hatnote".

File:Xanax (alprazolam) 2 mg.jpg
Xanax is an benzodiazepine used as a trip killer.

Medical treatment consists of supportive therapy and minimization of external stimuli. In some cases, sedation is used when necessary to control self-destructive behavior, or when hyperthermia occurs. A trip killer such as alprazolam, diazepam, quetiapine, or trazodone is the most frequently used treatment.[7] Other benzodiazepines such as lorazepam are also effective. Such sedatives will only decrease fear and anxiety, but will not subdue hallucinations. Antipsychotics such as quetiapine, aripiprazole, risperidone, and haloperidol can reduce or stop hallucinations. Haloperidol is effective against acute intoxication caused by LSD and other tryptamines, amphetamines, ketamine, and phencyclidine.[8][9]

Pathophysiology

Bad trips may cause range of conditions such as psychosis and hallucinogen persisting perception disorder (HPPD).[10]

Perspectives

Stanislav Grof

Psychiatrist Stanislav Grof once said in an interview:

<templatestyles src="Template:Blockquote/styles.css" />

There is a tremendous danger of confusing the inner world with the outer world, so you'll be dealing with your inner realities but at the same time you are not even aware of what's happening, You perceive a sort of distortion of the world out there. So you can end up in a situation where you're weakening the resistances, your conscious is becoming more aware, but you're not really in touch with it properly, you're not really fully experiencing what's there, not seeing it for what it is. You get kind of deluded and caught into this.[11]

Script error: No such module "Check for unknown parameters".

In a 1975 book, Grof suggested that painful and difficult experiences during a trip could be a result of the mind reliving experiences associated with birth, and that experiences of imprisonment, eschatological terror, or suffering far beyond anything imaginable in a normal state, if seen through to conclusion, often resolve into emotional, intellectual and spiritual breakthroughs. From this perspective, Grof suggests that interrupting a bad trip, while initially seen as beneficial, could potentially trap the tripper in unresolved psychological states. Grof also suggests that many cathartic experiences within psychedelic states, while not necessarily crises, may be the effects of consciousness entering a perinatal space.[12]

Rick Strassman

Professor of psychiatry Rick Strassman is critical of reframing the experience of bad trips as one of "challenging experiences".[13]

See also

References

Template:Reflist

External links

Template:Medical resources

Template:Psychoactive substance use

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