Rostral interstitial nucleus of medial longitudinal fasciculus
Script error: No such module "Infobox".Template:Template otherScript error: No such module "Check for unknown parameters".Script error: No such module "Check for unknown parameters". The rostral interstitial nucleus of medial longitudinal fasciculus (riMLF) is a collection of neurons in the medial longitudinal fasciculus in the midbrain.[1] It is responsible for mediating vertical conjugate eye movements (vertical gaze)[1][2]Template:Rp and vertical saccades.[3]Template:Rp It mostly projects efferents to the ipsilateral oculomotor and trochlear nuclei.[2]Template:Rp
To mediate downgaze, it projects efferents to the ipsilateral oculomotor nucleus and trochlear nucleus; mediate upgaze,[2]Template:Rp it projects efferents to the contralateral aforementioned nuclei[3]Template:RpTemplate:Additional citation needed through the posterior commissure.[2]Template:Rp
It is one of the accessory oculomotor nuclei.[3]Template:Rp
Anatomy
Structure
The riMLF is a wing-shaped nucleus.[2]Template:Rp
The riMLF contains two populations of neurons: excitatory burst neurons mediating vertical gaze/saccades, as well as omnipause neurons which are functionally similar to those mediating horizontal gaze.[2]Template:Rp
Relations
It is situated at the caudal extremity of the mesencephalon[1] at its junction with the telencephalon,[3]Template:Rp at the level of the superior colliculus.[1] It is situated dorsal to the rostral extremity of the red nucleus, and rostral to the interstitial nucleus of Cajal.[2]Template:Rp
Clinical significance
Lesions of the riMLF may impair vertical gaze completely, or predominately impair downgaze.[2]Template:Rp Lesions of the posterior commissure meanwhile disrupt upgaze.[2]Template:Rp
See also
- Interstitial nucleus of Cajal - another structure involved in vertical gaze (including torsional gaze and gaze holding, but not saccades).
- Paramedian pontine reticular formation - the horizontal gaze center.
References
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