Talk:Situs inversus

prevalence

The e-medicine article suggest 0.01% (1 in 10,000) of population is afflicted with Situs inversus, we appear to use this statistic. http://healthlink.mcw.edu/article/901226430.html suggests 1 in 7000 to 8000 is afflicted. Which shall we use? --OldakQuill 19:57, 6 May 2004 (UTC)

• 0.01% might be a rounded figure. Fredrik 20:19, 6 May 2004 (UTC)
• This page gives 1:8500. Ksheka 13:02, May 8, 2004 (UTC)
• This page suggests 2 out of 118,012 patients, whereas this one suggests 1 in 8,000. Well, it's rare, just exactly how rare I'm not sure ... Alex.tan 18:37, 9 May 2004 (UTC)

background

The developmental biology of Situs inversus must be governed by the action potential which orders the formation of the tissues of the inverted organs. Ancheta Wis 03:10, 7 May 2004 (UTC)

In particular, the heart is really a spiral of muscle (see Hermann Weyl's book on Symmetry; thus the heart in Situs inversus may be also a inverted spiral as well) Ancheta Wis 03:10, 7 May 2004 (UTC)

When a genetic marker for this condition is discovered, it ought to be possible to detect a difference in action potential during the transition from morula to blastula, as compared to the usual development stages.Ancheta Wis 10:25, 7 May 2004 (UTC)

I've got a book at home with loads on the history of how situs invertus was first discovered. If I get time over the weekend (which actually is probably unlikely) I'll add it in. Otherwise, if anyone wants to look it up and do it themselves, the book is Left Hand, Right Hand (and there's plenty of info at the book's website). --ALargeElk 13:36, 7 May 2004 (UTC)

What is actually missing is an attempt to explain this down to the molecular reasons for this. After all, everyone starts as a single cell, so the development for a situs inversus must have something remarkable, and I am sure this was described in detail already. Now only wikipedia needs to get this info... ;) 80.108.103.172 (talk) 02:03, 9 September 2009 (UTC)

images

Does anyone know of any free images of this? I suppose mirroring regular x-rays won't do. Fredrik 09:47, 10 May 2004 (UTC)

why not ;-) e 02:05, 11 May 2004 (UTC)

File:Heart-and-lungs.jpg

- Mirror this? (and remove labels)Bensaccount 04:18, 13 May 2004 (UTC)

urg... a good start, but I'm not personally a fan of those old gray's images - all that texture hides the point... anybody got anything clearer? don't forget it affects the abdomen as well. --e 14:20, 13 May 2004 (UTC)

I'm not sure it's the best picture, but here's the reversed version with labels removed in case a better one isn't found. Angela. 21:58, May 13, 2004 (UTC)

File:Situs inversus - Mirrored heart and lungs.jpg

anatomy

I do not at all understand the meaning of this: Individuals with situs inversus that require transplantation of solid organs (e.g., the liver) may have issues regarding managing the altered anatomy they present with. "Regarding managing" and "present with" aren't even proper English, I think, but I don't understand this well enough to clarify it. Also, I think it'd be nice to know something more about these issues. Nickptar 00:29, 11 May 2004 (UTC)

this is just a 'left' shoe on 'right' foot problem - could be said clearer tho. e 02:05, 11 May 2004 (UTC)

The syntax "presents with" is normal doctor-speak. As for the rest, Erich gasboy|e is right. Blood vessels and nerves don't quite match up. Teflon Don 03:33, 13 April 2007 (UTC)

Teflon Don is right. The problem is the fact that the nerves and blood vessels don't match up. In order to get a heart transplant, a person with situs inversus would have to get a heart from someone else with the same condition.

Can someone please delete the UNM student from historical people?

It's like me putting my name under cystinuria. —The preceding unsigned comment was added by 139.225.163.202 (talk) 23:31, 5 May 2007 (UTC).139.225.163.202 23:31, 5 May 2007 (UTC)

handedness?

Are situs inversus people more likely to be left-handed (because the more common right-handedness gets switched to the other side)? Thanks, 68.6.41.238 04:23, 10 November 2007 (UTC)

I have situs inversus with dextrocardia and am right handed... so i dunno if it affects everyone else, but not myself. 198.108.80.10 (talk) 02:00, 4 September 2008 (UTC)Alex

In a word, yes. However, as you can see, not all are left-handed. HairyWombat (talk) 17:57, 5 June 2010 (

i also have situs inversus totalis with dextrocardia and i am left handed. my question is, why do i do everything backwards. for example: i play a right handed guitar-left handed, without reversing the strings (like jimi hendrix). i write left handed, throw left handed, and i do most things left handed. but there are alot of things i do really well right handed like battin, golfing, my right arm is stronger than my left. another question is, my fiance' and i recently found out that she is pregnant... what is the likelyhood that our child will have my disorder and shes not a carrier. i also had a VSD repair in 1991 and i was born with it. thank you :) george doherty gloucester ma.

Since people without this condition may be left or right handed and it's not uncommon for someone to bat or play guitar opposite their normally dominant hand, individual anecdotes aren't sufficient to answer this question. We'd really have to look at percentage of right and left-handedness for those with this condition vs those without to determine if this condition reverses 'handedness' or not. — Preceding unsigned comment added by Neonpolaris (talk • contribs) 16:58, 8 July 2015 (UTC)

It would seem not: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1691902/ — Preceding unsigned comment added by Neonpolaris (talk • contribs) 17:01, 8 July 2015 (UTC)

Chances of inheritance

Since our only child was born with situs inversus totalis does this mean that when we decide to have another one that he/she will have it to? —Preceding unsigned comment added by 70.128.10.153 (talk) 04:07, 28 September 2008 (UTC)

If neither of you have it then your odds of having another child with it are 1 in 4 but 3/4 of your kids will be carriers. If one of you has it you have a 50-50 chance for any other children and all your kids will be carriers. If both of you have it all of your children will also. This is what is meant by autozomal recessive. —Preceding unsigned comment added by 208.66.14.94 (talk) 19:39, 28 November 2009 (UTC)

My son has Situs Inversus Totalis with PCD(primary ciliary dyskenesia). Which all together are called Kartagener's syndrome. I have been told by my doctors that, Inheritance of the condition where both parents are carriers is 1/4 chance as it is a recessive gene. A 2/4 chance of children being carriers and 1/4 chance of non carrier(non affected). If the above people have a child with the condition it suggests they both have the gene either as a carrier or as affected. — Preceding unsigned comment added by 93.107.207.162 (talk) 22:18, 17 April 2012 (UTC)

Enrique Iglesias

From descriptions in the Enrique Iglesias article, it seems that statements by Mr. Iglesias regarding his anatomy should not be taken seriously. Absent other evidence, I don't think he should be included in the list of notable people with this condition. Perhaps he could be included as a fictional character? Cstaffa (talk) 22:04, 20 April 2009 (UTC)

Per WP:BLP, since there was no source, I removed the mention of him from this article, along with two other unsourced names. Situs inversus is (no longer?) mentioned in the Enrique Iglesias article, but it does mention that "Iglesias is very well known for not taking the media seriously and has consistently joked about a wide variety of matters", so it seems unlikely that he should be listed here. Siawase (talk) 11:57, 12 May 2009 (UTC)

Harmful?

Apart from potential complications with diagnosis or organ transplation, does situs inversus cause any medical problems, or does the reversed anatomy function normally? —Preceding unsigned comment added by 164.111.174.183 (talk) 15:42, 16 July 2009 (UTC)

Providing the situs inversus is complete then everything functions normally. People with situs inversus live just as long as people without this condition. HairyWombat (talk) 01:38, 10 July 2010 (UTC)

Heart transplant

53 year old Jack Eigel, with Situs Inversus, recently had a normal heart transplanted. http://abcnews.go.com/GMA/reversed-organs-miracle-heart-transplant-man-situs-inversus/Story?id=8629850&page=1

The Plattner Story

Just thought id mention that The Platner Story by H.G. wells was also about a man with Situs Inversus —Preceding unsigned comment added by 72.25.192.4 (talk) 00:26, 7 October 2009 (UTC)

Ninja Assassin

In the recent film, "Ninja Assassin," staring Korean film singer Rain and the great Sho Kosugi, situs plays a prevalent role in the plot. (SPOILER WARNING!!!) An early reveal features an old man that once survived a ninja attack serendipitously due to the condition. This is a set-up to justify the eventual survival of another key character (female) due to the same condition. This would make a valid addition to the "in fiction" section. 67.161.39.188 (talk) 08:58, 1 December 2009 (UTC)

Only living case ?

This report [1] in telegraph.co.uk says a '64-year-old could be the only man in the world whose internal organs are in the mirror opposite position of where they should be' and this 'is thought to be the only living case of "situs inversus".' But going by the article this is not so rare. Did telegraph.co.uk get the name wrong or is there a even more rarer sub-category of the condition ? --Mgtm7m (talk) 15:34, 11 February 2010 (UTC)

This is not just a case of situs inversus; the newspaper reporter got it wrong. The patient has no small intestine, two livers, plus other abnormalities. HairyWombat (talk) 18:05, 5 June 2010 (UTC)

Thanks for the clarification -Mgtm7m (talk) 09:37, 15 June 2010 (UTC)

Preocupante?

Hello I'm Deborah varca are in Turin and I have 20 years I have discovered the statum viscerum inversum the age of 13 years does not mean anything preocupante true?—Preceding unsigned comment added by 95.244.88.80 (talk) 15:08, 9 June 2010 (UTC)

Google translates "preocupante" as "some worrying". If your situs inversus viscerum is complete then no, there is no need to worry. People with situs inversus live just as long as people without this condition. If you ever need major surgery then make sure they know, and if you ever need an organ transplant then there can be problems as the new organ may not "fit". HairyWombat (talk) 01:11, 10 July 2010 (UTC)

Overabundance of Fictional Examples

The length of the fictional examples of characters with this condition is nearly as long as the rest of the content of the article. That seems excessive. What's the guideline on stuff like this? You sure as heck don't make a list of everyone in fiction with, say, blue eyes. 76.98.145.131 (talk) 19:36, 29 October 2010 (UTC)

Image regarding situs inversus and KS

Since the editor seems pretty adamant about inserting the image, I wanted to see if perhaps it was just me. Is this accurate? Before removing the image for a third time, I wanted to try to discuss this, and if I'm wrong, awesome, I'll stop removing the image, but from my understanding, this description is inaccurate. I didn't see any sources supporting the description that situs inversus is "due to" KS, and to my understanding, KS is defined by the presence of situs inversus, situs inversus is never "caused by" KS. - SudoGhost 15:04, 29 January 2012 (UTC)

It's not just you. KS is a syndrome which includes SI; it's not a cause of SI. In any case, I doubt that the image should be used, as the text error has been embedded within the image itself, and the latter is identified as "own work" (student? patient?). It seems preferable, imho, to illustrate the article using images and descriptors from reliable medical sources. Haploidavey (talk) 15:17, 30 January 2012 (UTC)

The user has returned from being blocked to continue to reinsert the image without discussion, so I thought I'd comment on this. The user is apparently inserting a new version of the image without the "KS causes SI" wording, but I agree that an image that is one's "own work" doesn't really belong on the article when there are images from reliable medical sources available, and certainly not without any sort of discussion first. - SudoGhost 02:43, 3 February 2012 (UTC)

It's good to see a positive response to concerns over text but I can't see that such a complex assembly of tiny images helps the average reader to grasp the topic. It seems to illustrate a KS case study; SI plus pathological signs (COPD (bronchiectasis?), KS-related heart-trace abnormalities}, and a part-labelled cross-sectional CT showing typical SI reversals - we already have one of those on the page. As the image seems tied to KS, rather than SI, it might be useable at the KS article. Btw, a bot has asked the user to clarify the image's source and status. So far, there's been no response to that or any other requests and messages at the user's talk-page. Haploidavey (talk) 12:33, 3 February 2012 (UTC)

File:Kartagener syndrome.png Nominated for speedy Deletion

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External links modified

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Randy Foye

Not all his organs are reversed, only the abdominal organs. --Dr. Hartwig Raeder (talk) 14:40, 10 April 2019 (UTC)

Situs inversus is not situs ambiguus, situs ambiguus is not situs inversus

According to the source https://ghr.nlm.nih.gov/condition/heterotaxy-syndrome situs solitus is normal organ distribution, situs inversus – mirror image. Situs ambiguous is everything in between. So Rose Marie Bentley was not situs inversus 1. She was not mirror image. 2. She had some isomerism characteristics, typical for heterotaxy, for example, her right and left lungs both had only two lobes. 3. She had abnormal vessel anatomy and not so typical right atrium. The fact that CNN named her situs inversus does not make her one. Kublakuzz (talk) 13:07, 12 April 2019 (UTC)

We rely on published, reliable sources here. Multiple of these sources, as well as the staff of Oregon Health and Sciences University who examined her cadaver, have described Bentley's condition as "Situs inversus with levocardia". Unless you can find a reliable published source that describes her condition as something other than that, the inclusion of Bentley among notable cases of situs inversus will stay. General Ization ^Talk 13:13, 12 April 2019 (UTC)

"situs inversus incompletus" - did they give up and made-up "incompletus" ?

It sounds like really bad slang, a comedian impersonating the Latin language or something along those lines.

If it is indeed correct. this post can be ignored. — Preceding unsigned comment added by 77.105.212.140 (talk) 18:14, 11 April 2021 (UTC)

Basic Sc

List The Organs Invosrred In Digastive Systam — Preceding unsigned comment added by 41.190.2.218 (talk) 20:04, 13 January 2023 (UTC)

Handedness

The paragraph on handedness says "Situs inversus does not appear to significantly affect rates of handedness." but then also says "A more recent 2023 study failed to find statistically significant differences in cognition, albeit left-handedness was significantly more common at 26% compared to the 10.6% of general population." -- this seems to be a contradiction? CapitalSasha ~ talk 15:39, 12 October 2024 (UTC)