Synaptic pharmacology
Jump to navigation
Jump to search
Script error: No such module "Unsubst". Synaptic pharmacology is the study of drugs that act on the synapses. It deals with the composition, uses, and effects of drugs that may enhance (receptor) or diminish (blocker) activity at the synapse, which is the junction across which a nerve impulse passes from an axon terminal to a neuron, muscle cell, or gland cell.
A partial list of pharmacological agents that act at synapses follows.
| Channel, Receptor, or Phenomenon | Antagonist or Blocker |
|---|---|
| adenosine | DCPGX, ZM241385, anoxinine |
| AMPA-R | NBQX |
| AMPA-R desensitization | cyclothiazide (CTZ) |
| cannabinoid | AM-251 |
| GABAA | bicuculline,[1] gabazine[1] |
| GABAB | CGP-54626 |
| glycine | strychnine |
| kainate R | .. |
| metabotropic GluR, broad | MCPG,[2] pertussis toxin, NEM |
| muscarinic AChR | atropine, Scopolamine |
| nicotinic AChR | bungarotoxin, curare, DhBe |
| NMDA-R | APV |
References
<templatestyles src="Reflist/styles.css" />
Script error: No such module "Check for unknown parameters".