Prostaglandin E synthase

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Prostaglandin E synthase (Template:EnzExplorer, or PGE synthase) is an enzyme involved in eicosanoid and glutathione metabolism, a member of MAPEG family. It generates prostaglandin E (PGE) from prostaglandin H2.[1][2]

The synthase generating PGE2 is a membrane-associated protein.

File:Eicosanoid synthesis.svg
Biosynthesis of eicosanoids.

Isozymes

Humans express three prostaglandin-E synthase isozymes, each encoded by a separate gene:

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References

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External links

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