OS9 (gene)

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Template:Short description Template:Infobox gene Protein OS-9 is a protein that in humans is encoded by the OS9 gene.[1][2][3][4][5]

Function

This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[5]

References

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Further reading

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