Enolase 2

From Wikipedia, the free encyclopedia
(Redirected from Neuron-specific enolase)
Jump to navigation Jump to search

Template:Short description Template:Cs1 config Template:Infobox gene Gamma-enolase, also known as enolase 2 (ENO2) or neuron specific enolase (NSE), is an enzyme that in humans is encoded by the ENO2 gene.[1][2] Gamma-enolase is a phosphopyruvate hydratase.

Gamma-enolase is one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.[1]

Interactive pathway map

Template:GlycolysisGluconeogenesis WP534

Utility

File:Hemangioblastoma - nse - high mag.jpg
Neuron-specific enolase (NSE) immunostaining of a cerebellar hemangioblastoma.

Detection of NSE with antibodies can be used to identify neuronal cells and cells with neuroendocrine differentiation. NSE is produced by small-cell carcinomas, which are neuroendocrine in origin. NSE is therefore a useful tumor marker for distinguishing small-cell carcinomas from other tumors.[3]

References

<templatestyles src="Reflist/styles.css" />

  1. ↑ a b Script error: No such module "citation/CS1".
  2. ↑ Online Mendelian Inheritance in Man (OMIM): Enolase 2 - 131360
  3. ↑ Script error: No such module "Citation/CS1".

Script error: No such module "Check for unknown parameters".

Further reading

<templatestyles src="Refbegin/styles.css" />

  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".
  • Script error: No such module "Citation/CS1".

External links

Template:PDB Gallery Template:Carbon-oxygen lyases Script error: No such module "Navbox". Template:Portal bar Script error: No such module "Navbox".

Retrieved from "http://debianws.lexgopc.com/wiki143/index.php?title=Enolase_2&oldid=5932115"