N-Formylpiperidine
(Redirected from N-formylpiperidine)
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| Template:Longitem | 107697 |
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| MeSH | N-Formylpiperidine |
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| UN number | 2810 |
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| Density | 1.019 g cm−3 |
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| Vapor pressure | 0.01 kPa |
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N-Formylpiperidine is an organic compound with the formula C6H11NO. It is the amide of formic acid and piperidine. It can be used as a polar aprotic solvent, with better hydrocarbon solubility than other amide solvents such as dimethylformamide (DMF).[1] It has also been used to transfer the formyl group to a Grignard reagent:[2]
- PhCH2CH2MgCl + C6H11NO → PhCH2CH2CHO
In some formylation reaction of alkyllithium compounds, N-formylpiperidine gives higher yields than the DMF.[3]
References
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