Benign lymphoepithelial lesion
Template:Infobox medical condition (new) Benign lymphoepithelial lesion or Mikulicz' disease is a type of benign enlargement of the parotid and/or lacrimal glands. This pathologic state is sometimes, but not always, associated with Sjögren's syndrome.
Signs and symptoms
Treatment
Eponym
Historically, bilateral parotid and lacrimal gland enlargement was characterized by the term Mikulicz's disease if the enlargement appeared apart from other diseases. If it was secondary to another disease, such as tuberculosis, sarcoidosis, lymphoma, and Sjögren's syndrome, the term used was Mikulicz's syndrome. Both names derive from Jan Mikulicz-Radecki, the Polish surgeon best known for describing these conditions.[1][2]
In more recent times, the terms "Mikulicz's disease" and "Mikulicz's syndrome" were viewed as ambiguous and outdated by some sources.[3]
Today Mikulicz's disease is considered to be a subtype of IgG4-related disease, usually accompanied by involvement of one or more other organs in the body.[4]
See also
References
Further reading
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External links
- [https://rarediseases.org/rare-diseases/mikulicz-syndrome/ Mikulicz syndrome on The National Organization for Rare Disorders (NORD)
- Benign lymphoepithelial lesions on Radiopedia
- ↑ synd/2087 at Whonamedit? – "Mikulicz's disease"
- ↑ synd/2088 at Whonamedit? – "Mikulicz's syndrome"
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