Lutetium(III) chloride

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Lutetium(III) chloride or lutetium trichloride is the chemical compound composed of lutetium and chlorine with the formula LuCl3. It forms hygroscopic white monoclinic crystals[1] and also a hygroscopic hexahydrate LuCl3·6H2O.[2] Anhydrous lutetium(III) chloride has the YCl3 (AlCl3) layer structure with octahedral lutetium ions.[3]

Lutetium-177, a radioisotope that can be derived from lutetium(III) chloride, is used in targeted cancer therapies.[4] When lutetium-177 is attached to molecules that specifically target cancer cells, it can deliver localized radiation to destroy those cells while sparing surrounding healthy tissue.[5] This makes lutetium-177-based treatments especially valuable for cancers that are difficult to treat with traditional methods, such as neuroendocrine tumors and prostate cancer.[6] Additionally, lutetium(III) chloride is used in scintillators, materials that emit light when exposed to radiation.[7] These scintillators are crucial in detectors for gamma rays and other high-energy particles, used in both medical diagnostics and in scientific research.[8]

Reactions

Pure lutetium metal can be produced from lutetium(III) chloride by heating it together with elemental calcium:[9]

2 LuCl3 + 3 Ca → 2 Lu + 3 CaCl2

See also

References

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