Initiation-specific alpha-1,6-mannosyltransferase

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Template:Short description Template:Infobox enzyme In enzymology, an initiation-specific alpha-1,6-mannosyltransferase (EC 2.4.1.232) is an enzyme that catalyzes the chemical reaction in which an alpha-D-mannosyl residue is transferred from GDP-mannose to a lipid-linked oligosaccharide, being linked by an alpha-1,6-D-mannosyl-D-mannose bond.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:oligosaccharide 1,6-alpha-D-mannosyltransferase. Other names in common use include alpha-1,6-mannosyltransferase, GDP-mannose:oligosaccharide 1,6-alpha-D-mannosyltransferase, GDP-mannose:glycolipid 1,6-alpha-D-mannosyltransferase, and glycolipid 6-alpha-mannosyltransferase. This enzyme participates in high-mannose type n-glycan biosynthesis.

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