David Mervyn Blow
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David Mervyn Blow Template:Post-nominals[1] (27 June 1931 – 8 June 2004)[2][3][4] was an influential British biophysicist. He was best known for the development of X-ray crystallography, a technique used to determine the molecular structures of tens of thousands of biological molecules. This has been extremely important to the pharmaceutical industry.[5]
Early life and education
Blow was born in Birmingham, England. He was educated at Kingswood School in Bath, Somerset and the University of Cambridge where he won a scholarship to Corpus Christi College, Cambridge. His PhD was awarded in 1958 for X-ray analysis of haemoglobin supervised by Max Perutz at the MRC Laboratory of Molecular Biology (LMB).[6][7]
Career and research
Following graduation from Cambridge, Blow spent two years at the Massachusetts Institute of Technology (MIT) and the National Institutes of Health (NIH) funded by the Fulbright Foundation[2]
In 1954, he met Max Perutz;[8] they began to study a new technique wherein X-rays would be passed through a protein sample at the MRC Laboratory of Molecular Biology. This eventually led to the creation of a three-dimensional structure of haemoglobin.[9] Blow was appointed professor of biophysics at Imperial College London in 1977. His doctoral students include Richard Henderson,[10][11] Paul Sigler,[12] and Alice Vrielink.[13]
Awards and honours
Blow was elected a Fellow of the Royal Society (FRS) in 1972. He was awarded the Wolf Prize in Chemistry in 1987.[2]
Personal life
Blow married Mavis Sears in 1955, and they had two children, a son Julian and a daughter Elizabeth.[2][4] He died of lung cancer at the age of 72, in Appledore, Torridge (near Bideford), Devon.[3][4]
References
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- 1931 births
- 2004 deaths
- Academics of Imperial College London
- Alumni of Corpus Christi College, Cambridge
- Deaths from lung cancer in England
- English biophysicists
- Fellows of the Royal Society
- Fellows of the Institute of Physics
- Members of the French Academy of Sciences
- People educated at Kingswood School, Bath
- Scientists from Birmingham, West Midlands
- Wolf Prize in Chemistry laureates
- Massachusetts Institute of Technology faculty
- Deans of the Royal College of Science
- Presidents of the British Crystallographic Association