CMAS (gene)
Template:Cs1 config Template:Short description Template:Infobox gene N-acylneuraminate cytidylyltransferase is an enzyme that in humans is encoded by the CMAS gene.[1][2][3]
Function
The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.[3]
References
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External links
Further reading
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