Integrin alpha 5
Template:Short description Template:Cs1 config Template:Infobox gene Integrin alpha-5 is a protein that in humans is encoded by the ITGA5 gene.[1]
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.[2]
Interactions
ITGA5 has been shown to interact with GIPC1.[3]
See also
References
<templatestyles src="Reflist/styles.css" />
Script error: No such module "Check for unknown parameters".
Further reading
<templatestyles src="Refbegin/styles.css" />
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
External links
- Template:MeshName
- ITGA5 Info with links in the Cell Migration Gateway Template:Webarchive
- Template:PDBe-KB2
Script error: No such module "Navbox". Template:Integrins